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DXM (Dextromethorphan) is a drug of the morphinan class with sedative, dissociative, and stimulant properties.
DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist. The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist. In high doses this produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetic. As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of Dextromethorphan.
Alias: Dextromethorphan Hbr, Dextromethorphan Hydrobromicum, Dextromethorphan Hydrobromide, Romilar, Dextromethorphan Hydrobromide
CAS No.: 125-69-9
MF: C18H26BrNO
Purity: 99.0%
Appearance: White or kind of white crystalline powder
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